Pathophysiology Osteoarthritis (OA) is characterised by the breakdown of cartilage and underlying bone within the joint. Other structures also are affected by OA, with inflammation of the synovium and narrowing of the joint space commonly seen. The ligaments surrounding the joint may also be effected becoming thickened and fibrotic. Although there is not one distinct … Continue reading Osteoarthritis: What it is and how we can help